| TEAM | 1Q | 2Q | 3Q | 4Q | OT | FINAL | |
 | Southern Miss (0-2) | 0 | 14 | 0 | 7 | 0 | 21 |  |
Louisville (2-0) | 14 | 6 | 0 | 6 | 0 | 26 |
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| Team Statistics | USM | LOU |
| First Downs | 15 | 28 |
| Rushing | 5 | 7 |
| Passing | 9 | 19 |
| Penalty | 1 | 2 |
| 3rd-down Efficiency | 6-15 | 5-15 |
| 4th-down Efficiency | 0-0 | 0-0 |
| Total Net Yards | 313 | 495 |
| Total plays | 65 | 84 |
| Average gain | 4.8 | 5.9 |
| Net Yards Rushing | 61 | 176 |
| Rushes | 29 | 47 |
| Average per rush | 2.1 | 3.7 |
| Net Yards Passing | 252 | 319 |
| Completed-attempted | 19-35 | 25-33 |
| Yards per pass | 7.2 | 9.7 |
| Sacked-yards lost | 1-5 | 4-10 |
| Had intercepted | 1 | 0 |
| Punts-average | 9-47.7 | 7-39.4 |
| Return Yardage | 134 | 125 |
| Punts-returns | 2-29 | 3-63 |
| Kickoffs-returns | 5-105 | 2-60 |
| Interceptions-returns | 0-0 | 1-2 |
| Penalties-yards | 3-30 | 7-33 |
| Fumbles-lost | 2-1 | 0-0 |
| Touchdowns | 3 | 4 |
| Rushing | 0 | 0 |
| Passing | 3 | 4 |
| Extra Points | 3-3 | 2-3 |
| Field Goals | 0-0 | 0-2 |
| Red Zone Efficiency | 2-2-100% | 2-4-50% |
| Time Of Possession | 26:02 | 33:58 |
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| First Quarter |
| LOU | TD | 13:14 | 7-0 | Gregg Ferguson 30 YD Pass from James Kendall (Patrick Jervey Kick). |
| LOU | TD | 08:25 | 14-0 | Gustavo Shaw 11 YD Pass from James Kendall (Patrick Jervey Kick). |
| Second Quarter |
| LOU | TD | 13:25 | 20-0 | Gregg Ferguson 30 YD Pass from James Kendall (Patrick Jervey Kick Failed). |
| USM | TD | 10:08 | 20-7 | Gavin Solis 9 YD Pass from Aaron Coon (Joshua Edwards Kick). |
| USM | TD | 02:57 | 20-14 | Conor McFadden 53 YD Pass from Aaron Coon (Joshua Edwards Kick). |
| Fourth Quarter |
| LOU | TD | 03:38 | 26-14 | Corey Redmon 2 YD Pass from James Kendall (2 Pts Failed) |
| USM | TD | 00:47 | 26-21 | Vyto Wallace 13 YD Pass from Aaron Coon (Joshua Edwards Kick). |
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| USM PUNTING |
| NO | AVG | NET | I-20 | TB | LG |
| P N. Lipps | 9 | 47.70 | 40.70 | 3 | 0 | 56 |
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| LOU PUNTING |
| NO | AVG | NET | I-20 | TB | LG |
| P Z. Dodds | 7 | 39.40 | 35.30 | 0 | 0 | 54 |
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| Player of the Game |
 | James Kendall, Quarterback |
| CP/AT | Yards | TD | INT | RUSH |
| 25/33 | 319 | 4 | 0 | -1 |
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| Game Information |
| Attendance: 48,526 |
| Temperature: 83 |
| Weather: Slightly overcast |
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